All cells in the body secrete exosomes. Exosomes from the prostate are called prostasomes. Exosomes act as messengers between the body’s cells. The exosome always carries traces of its parent cell. If a person has prostate cancer, there are traces of it in the prostasomes.
How exosomes arise
In the membrane that surrounds all cells, there are certain areas called lipid rafts. At these rafts, the membrane bulges into the cell (invagination) and detaches to form a vesicle. The process is repeated several times in the new vesicle, whereby a vesicle containing many vesicles (endosomes), forms a multivesicular body (MVB). The quirk of double invagination is that the exosomes will have the same side out as the original cell membrane.
DNA, RNA and proteins in the cell are transported to the exosomes via special sorting mechanisms. The MVB vesicle then fuses with the cell wall, releasing the contents i.e exosomes outside the cell. That’s when the vesicle becomes an exosome. In a healthy person, the prostasomes exit the glandular duct and carry messages to the recipient cell via the seminal fluid.